Hydrogen-induced degradation is a critical challenge in the performance of materials under mechanical stress, particularly in environments where hydrogen uptake occurs. This study focuses on investigating the effects of hydrogen on microbending beam fatigue and micromechanical behavior, with an emphasis on nanoindentation under hydrogen-charged conditions. The research explores hydrogen charging via two distinct methods: electrochemical hydrogen charging, applied to both the front and backside of material samples, and plasma hydrogen charging, enabling in-situ mechanical testing within a scanning electron microscope (SEM). These investigations are combined with results from meso- and macroscale testing under hydrogen expore. The scale-bridging experimental approach aims to provide a detailed understanding of the hydrogen's influence on plastic deformation of metals as well as metal fatigue at the micro- and nanoscale. By examining the mechanical response of materials subjected to cyclic loading in the presence of hydrogen, the study will contribute to understanding the mechanisms of hydrogen-metal interaction, especially hydrogen-dislocation interaction. The results will also serve to compare the effectiveness of different hydrogen charging methods on material degradation and mechanical failure, advancing knowledge in the field of micro- and nanomechanics in hydrogen environments.